Publications
Governing the AI-biotech convergence
Publication for Science & Society
The convergence of AI and biotechnology is driving a revolution in biological engineering, but it is also creating a dangerous security gap. Because AI evolves at a lightning pace, it consistently outpaces the years-long process required to pass new government regulations. To close this gap, the authors advocate for adaptive and anticipatory governance: a flexible system designed to evolve alongside the science, ensuring that rapid progress never comes at the cost of safety, ethics, or global security.
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Benjamin D Trump, Christopher L Cummings, Beth Ellinport, Stephanie Galaitsi, Thomas Janisko, Elizaveta Pinigina, Hannah Herzig, Cindy S Groff-Vindman, Markus Schmidt, Gerald Epstein, Ruth Mampuys, Christian Haggenmiller, Tatyana Novossiolova, Travis Tubbs, James H Lambert, Alexander Titus & Igor Linkov
January 2026
Understanding the Complexity of Transcription Initiation in Prokaryotes
Review Article on Promoter Sequences
Promoter sequences are important genetic control elements. Through their interaction with RNA polymerase they determine transcription strength and specificity, thereby regulating the first step in gene expression. This article reviews the influence of promoter sequence on the mechanisms and kinetics of transcription initiation. This knowledge can be utilized in the development of a more rational approach to promoter engineering. It can help design more predictable, tuneable, and orthogonal promoter sequences, which is important in the context of regulation of gene expression and further, the development of robust microbial cell factories.
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Cara Deal, Lien De Wannemaeker and Marjan De Mey
March 2024
credit: Deal et al.
credit: Deal et al.